Here's a presentation which I gave recently at a [http://www.futurict.ethz.ch/FuturICT FuturICT] meeting about art-science as an interdisciplinary activity, and why I like to do it. (Note: updated version [http://www.mo-seph.com/presentations/art-science here])
I found this paper by Born and Barry inspiring while putting this together: [http://www.tandfonline.com/doi/abs/10.1080/17530351003617610 ART-SCIENCE: From public understanding to public experiment] (thanks [http://www.owengreen.net owen] and [http://sarahroberts.net/ sarah])